Osteochondrosis (OC) is a multifocal pathology, which takes place in both articular-epiphyseal cartilage complex (immature joint cartilage covering the ends of growing long bones) and growth plate in a variety of mammalian species. The disorder is characterized by failure of endochondral ossification, and is considered as one of the most common primary causes of degenerative joint disease in domestic animals [2, 3]. One of the most recurrent manifestations of OC is the osteochondrosis dissecans (OCD), which is considered to be involved in failure of cellular differentiation in growing cartilage, leading to its dramatic thickening or retention, emergence of fissures and eventual focal loss of cartilage flaps into the joint cavity. The detached fragments can be responsible of severe joint inflammation, which can lead to subsequent development of secondary osteoarthritis (OA) [4].
Physiology Of Domestic Animals Sjaastad Hove And Sand Pdf 107
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